Aquaculture Europe 2026

September 28 - October 1, 2026

Ljubljana, Slovenia

Add To Calendar 30/09/2026 15:45:0030/09/2026 16:00:00Europe/ViennaAquaculture Europe 2026FROM HISTORICAL OUTBREAKS TO MODERN INTERVENTIONS: CHRONICLING THE IMPACT OF Vibrio harveyi AND ESTABLISHING A STANDARDIZED INFECTION MODEL IN BARRAMUNDIUrska 4The European Aquaculture Societywebmaster@aquaeas.orgfalseDD/MM/YYYYaaVZHLXMfzTRLzDrHmAi181982

FROM HISTORICAL OUTBREAKS TO MODERN INTERVENTIONS: CHRONICLING THE IMPACT OF Vibrio harveyi AND ESTABLISHING A STANDARDIZED INFECTION MODEL IN BARRAMUNDI

Yin Min Thant1*, May Moh Moh Khin1, Giang Vo1, Khanh Nguyen1, Thanh Chau1, Loc Tran1

1 ShrimpVet Laboratory, Vietnam Acute vibriosis, driven by the halophilic bacterium Vibrio harveyi, represents one of the most critical microbiological threats to the expansion of global barramundi (Lates calcarifer) aquaculture. Characterized by severe hemorrhagic septicemia, deep dermal ulcerations, and rapid mortality, V. harveyi outbreaks frequently devastate nursery and grow-out operations. To develop effective prophylactic interventions, functional feeds, and therapeutic strategies, the establishment of a reproducible, robust, and standardized laboratory infection model is fundamentally required. The experimental immersion challenge was conducted at the ShrimpVet laboratory facilities using a hyper-virulent field strain of Vibrio harveyi. To initiate the challenge, the calibrated bacterial inoculum was introduced directly into the water column of the designated trial tanks. The precise exposure dosage was systematically calculated using ShrimpVet's internal calibration matrices, factoring in both the mean biomass and the specific weight of the fish cohorts at the time of challenge.

Email: yin.minthant@shrimpvet.com

 



Following exposure, real-time mortality trends and clinical signs were monitored at high-frequency intervals over post-infection monitoring period. Moribund and deceased individuals underwent immediate necropsy and bacteriological re-isolation to confirm Koch's postulates, establishing a robust, standardized benchmarking framework for downstream therapeutic screening.

Establishing such predictable mortality baseline minimizes experimental variability across treatment cohorts, ensuring high statistical reproducibility. It offers a valuable platform not only for validating natural phytogenic compounds—such as specialized organic acid formulations—but also for optimizing commercial bath immersion and injection-based vaccination schedules. Ultimately, this standardized protocol bridges the gap between controlled laboratory environments and commercial field conditions, advancing sustainable disease management strategies against vibriosis in global barramundi production.

Acknowledgment

The authors express their sincere gratitude to the experts and technicians at the ShrimpVet laboratory for their invaluable technical support, precise execution of the experimental protocols, and dedication.

References

1. Kumaran, Suresh & Balaraman, Deivasigamani & Kumarappan, Alagappan & Sakthivel, M. (2010). Infection and immunization trials of Asian seabass (Lates calcarifer) against fish pathogen Vibrio anguillarum. Journal of environmental biology / Academy of Environmental Biology, India. 31. 539-41.

2. Austin, B., & Austin, D. A. (2016). Bacterial Fish Pathogens: Disease of Farmed and Wild Fish (6th ed.). Springer International Publishing. https://doi.org/10.1007/978-3-319-32674-0.

3. Tendencia, E. A. (2002). Vibrio harveyi isolated from cage-cultured seabass Lates calcarifer Bloch in the Philippines. Aquaculture Research. https://doi.org/10.1046/J.1365-2109.2002.00688.

4. Mohamad, N., Amal, M. N. A., Yasin, I. S. M., Saad, M. Z., Nasir, N. M., Al-saari, N., & Mino, S. (2019). Vibriosis in cultured marine fishes: a review. Aquaculture, 512, 734289. https://doi.org/10.1016/j.aquaculture.2019.734289.

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